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WHERE DOES THE MONEY GO?

STOPPING CANCER CELLS’ PRO-SURVIVAL MECHANISMS IN TRIPLE-NEGATIVE BREAST CANCER

2019 - 2020

INSTITUTION:

The University of Sydney

 

CHIEF RESEARCHER:

Dr. Sumit Sahni

Development of novel therapy targeting autophagy against Triple-Negative Breast Cancers (TNBCs).

TNBC accounts for 15-20% of all breast cancers and is more common in young women. It can be more likely to spread and hard to treat. TNBC cells lack the three receptors - oestrogen, progesterone and HER2 - and so many of the standard therapies which target one of these receptors will not work. TNBCs are also highly likely to develop resistance to chemotherapy. Cancer cells can experience highly stressful conditions as a result of treatment with chemotherapeutic drugs and in order to escape the effects of treatment, cancer cells use a pro-survival pathway, known as autophagy. This can help cancer cells to grow and spread. Dr. Sumit Sahni will test new drugs to block autophagy, which he hopes will stop the growth and spread of TNBC and re-sensitise the cancer to anti-cancer drugs. Donated tissue samples will be used to learn more about the role of autophagy. Dr. Sahni is excited to bring his expertise in pancreatic cancer to the fight against breast cancer.

STOPPING CANCER CELLS’ PRO-SURVIVAL MECHANISMS IN TRIPLE-NEGATIVE BREAST CANCER

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Love Your Sister is Australia's hardest-working cancer vanquishing charity, and since its inception in 2012 has raised $20M for medical research.

 

Founded by Gold Logie-winning actor and Victorian Australian of the Year 2018, Samuel Johnson OAM, Love Your Sister is a million-strong village of everyday Aussies committed to vanquishing cancer with hard science and the best new technologies. Love Your Sister supports precision treatment for ALL cancer patients, whatever the cancer, regardless of location, age, income, or status. We strive for the right treatment for every cancer patient, first time, every time.

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oudly passes 100% of all donations received to research.  No skimming. No admin. No BS!

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